CV

Education

• Ph.D. in Biomedicine and Biotechnology, University of Valencia, Spain, 2019
• M.S. in Molecular, Cellular and Genetic Biology, University of Valencia, Spain, 2012
• B.S. in Biological Sciences, University of Valencia, Spain, 2011

Work experience

• October 2018 - Present: Postdoctoral Research Associate
  • MRC Laboratory of Medical Sciences (LMS) & Imperial College, London, UK
  • Supervisor: Prof. Filipe Cabreiro
• September 2012 - January 2019: PhD Researcher
  • Institute for Integrative Systems Biology (I2SysBio), Valencia, Spain
  • Supervisors: Prof. Andrés Moya Simarro & Dr. Carlos Peña Garay
• May 2016 - August 2016: Visiting Researcher
  • Albert Einstein College of Medicine, New York City, USA
  • Supervisor: Prof. Aviv Bergman

Skills

• Computational & Data Science
  • Languages: R (Advanced; Tidyverse, tidymodels), Python (Advanced; Pandas, Numpy, Scipy, Scikit-learn), Bash, Julia, MATLAB
  • Machine Learning: Keras, PyTorch, Tensorflow; applied experience with Protein Language Models and Attention Networks for pangenome analysis.
  • Tools & Environments: High-Performance Computing (HPC), SLURM, Linux, Git/GitHub, Jupyter Notebooks, Google Colab.
• Bioinformatics
  • Microbiome & Metagenomics: 16S rRNA analysis, Whole Genome Shotgun (WGS) metagenomics, functional analysis, community dynamics.
  • Genomics & Pangenomics: Microbial population genetics, pangenome analysis, microbial GWAS (mGWAS), genome assembly and functional annotation.
  • Multi-Omics Integration: Analysis and integration of RNA-seq, proteomics, and metabolomics data.
  • Databases & Phylogenetics: Database mining (NCBI, InterPro), phylogenetic reconstruction.
• Laboratory & Experimental
  • Model Organisms: Caenorhabditis elegans and Blattella germanica (maintenance, crossing, dissection, phenotyping).
  • Microbiology: Anaerobic culturing, strain library management, gene knockouts, Biolog characterization.
  • Molecular Biology: DNA/RNA extraction, PCR, plasmid transformation, sequencing preparation.

Publications

Chemotherapy modulation by a cancer-associated microbiota metabolite

Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms

Increased fidelity of protein synthesis extends lifespan

Development and implementation of a scalable and versatile test for COVID-19 diagnostics in rural communities

C. elegans: A biosensor for host-microbe interactions

Transcriptome analysis of Caenorhabditis elegans lacking heme peroxidase SKPO-1 reveals an altered response to Enterococcus faecalis

Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans

The role of the microbiome in drug response

Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy

Oxidative stress in the oral cavity is driven by individual-specific bacterial communities

Time series analysis of the microbiota of children suffering from acute infectious diarrhea and their recovery after treatment

Health and Disease Imprinted in the Time Variability of the Human Microbiome

Mining metagenomic whole genome sequences revealed subdominant but constant Lactobacillus population in the human gut microbiota

Talks

• Invited & Selected Talks
  • Navigating the E. coli pangenome to identify metformin drivers. The Local Pangenome, Alicante, Spain, Oct. 2023.
  • Microbiome in drug response: navigating the genetic landscape of the E. coli pangenome. Institute of Integrative Systems Biology (I2SysBio), Valencia, Spain, Apr. 2023.
  • Microbiome in drug response: navigating the genetic landscape of the E. coli pangenome. Pharmacogenetics and Stratified Medicine Network, London, UK, Jun. 2022.
  • Exploring the BGC potential in the E. coli pangenome. EMBO YIP, London, UK, Oct. 2021.
  • Metabolites at the interface of Microbe-Host physiology. LMS Chemistry Mixer, London, UK, Jun. 2019.
  • Application of Taylor’s Law to community ecology. ELSI Origins of Life EON, Tokyo, Japan, Jul. 2017.
  • Health and disease imprinted in the time variability of the human microbiome. V National Congress of Evolutionary Biology, Murcia, Spain, Jan. 2016.
• Conference Poster Presentations
  • Chemotherapy Modulation by a Cancer-Associated Microbiota Metabolite. Festival of Genomics & Biodata, London, UK, Jan. 2025.
  • A microbial metabolite controls cancer progression and chemotherapy. International Human Microbiome Consortium, Kobe, Japan, Nov. 2022.
  • Health and disease imprinted in the time variability of the human microbiome. 7th FEMS Congress, Valencia, Spain, Jul. 2017.
  • Individual-specific bacterial communities involved in the infection processes in the oral cavity. I National Congress of young researchers in Biomedicine, Valencia, Spain, Nov. 2016.
  • Temporal stability of the salivary microbiome and its correlation with oxidative markers. XIII Symposium on Bioinformatics, Valencia, Spain, May 2016.
  • Cyclic time variations in human microbiome. II Congress of PhD students of Biomedicine, Valencia, Spain, Nov. 2015.
  • Microbiota: are you sick? I Congress of PhD students of Biomedicine, Valencia, Spain, Nov. 2014.

Teaching

• (Co-)Mentored several BSc, Master’s, and PhD students at Imperial College London and I2SysBio.
• Founded and led a coding club for the research group, teaching essential bioinformatics skills.
• Served as a mock interviewer for the Early Career Researcher Initiative (ECRI) at Imperial College London.

Service and leadership

• Safety Supervisor for the Cabreiro Lab at MRC Laboratory of Medical Sciences (2018 - Present).
• Organizing Committee Member for the National Congress of Young Researchers in Biomedicine in Valencia (2015 - 2017).

Languages

• Mother Tongue: Spanish, Catalán
• Fluent: English
• Advanced: Portuguese
• Basic: Japanese